How Did Chemical Industries Come Into Being?

Industrial inorganic chemistry includes subdivisions ofcontrols on emissions. Sulfuric acid is manufactured as:
the chemical industry that manufacture inorganic2SO2 + O2 → 2SO3   ; SO3 + H2O → H2SO4
products on a large scale such as the heavySince the reaction of sulfur with dry air is exothermic,
inorganics (chlor-alkalis, sulfuric acid, sulfates) andthe sulfur dioxide must be cooled to remove excess
fertilizers (potassium, nitrogen, and phosphorusheat and avoid reversal of the reaction. Most plants
products) as well as segments of fine chemicals thatuse reactors with various stages in order to cool the
are used to produce high purity inorganics on a muchstream for the catalytic step. Conversion by a
smaller scale. Among these are reagents and rawvanadium pentoxide catalyst deposited on a silicate
materials used in high-tech industries, pharmaceuticalssupport is the critical step in the process, in which the
or electronics, for example, as well as in thegaseous stream is passed over successive layers of
preparation of inorganic specialties such as catalysts,catalyst. The gas mixture is then passed through an
pigments, and propellants. Metals are chemicals in aabsorption tower. Oleum, the product, is a
certain sense. They are manufactured from ores andconcentrated solution of sulfuric acid containing excess
purified by many of the same processes as thosesulfur trioxide.
used in the manufacture of inorganics. However, ifAs an inexpensive source of acid, a large amount of
they are commercialized as alloys or in their pure formthe sulfuric acid that is produced is used for the
such as iron, lead, copper, or tungsten, they aremanufacture of other mineral acids. It is also used to
considered products of the metallurgical not chemicalproduce sulfates, such as ammonium sulfate (a
industry.low-grade fertilizer), sodium sulfate (used in the
The chemical industry adds value to raw materials byproduction of paper), and aluminum sulfate (used in
transforming them into the chemicals required for thewater treatment), as well as organic sulfates (used as
manufacture of consumer products. Since there aresurfactants). Sulfuric acid is also a good catalyst for
usually several different processes that can be usedmany reactions, including the transformation of ethanol
for this purpose, the chemical industry is associatedinto ethylene or ethyl ether.
with intense competition for new markets. It is madeIn general, chemicals containing nitrogen are
up of companies of different sizes, including severalmanufactured from ammonia produced by the Haber
giants that are engaged in the transformation of someprocess. Since molecular nitrogen is inert, its reaction
very basic raw materials into final products, as well aswith hydrogen requires very severe conditions and a
medium-size or small companies that concentrate oncatalyst. An iron catalyst is used. High pressure favors
very few of these steps. The closer to the rawthe formation of products, but an increase in
material, the larger the scale of operations; suchtemperature will shift the equilibrium in the opposite
"heavy" inorganic chemicals are usually manufactureddirection. Plants will thus operate under conditions that
by continuous processes. At the other extreme inrepresent the most favorable balance between
terms of scale are the firms that manufactureoperating costs and capital investment. Energy
"specialties," mostly in batch processes, fromconsumption is very high, and its cost is an important
"intermediates" that correspond to chemicals whichcomponent along with the starting materials. Nitrogen is
have already gone through several steps of synthesiseasily obtained from air and hydrogen and can be
and purification.produced by the shift reaction: CO + H2O → CO2 +
Basic chemicals represent the starting point for theH2 or from hydrocarbon reforming: CH4 + 2H2O →
manufacture of inorganic industrial chemicals. They areCO2 + 4H2
usually one step away from the raw materials and areFurther stages are required to assure conversion and
produced on a very large scale employing continuousto remove carbon dioxide or carbon monoxide from
processes. The unit price of these products is relativelythe gas mixture. A mixture of ammonia and synthesis
low, and producing them cheaply and efficiently is agas (CO + H2) results from the reaction with nitrogen
major concern for the companies that manufactureso the two must be separated and the synthesis gas
them. Sulfur, nitrogen, phosphorus, and chloralkalirecycled.
industries are the main producers of basic inorganicMost of the ammonia that is produced is employed as
chemicals, and they will often sell them to otherfertilizer or used to manufacture other fertilizers, such
industries as well as using them in the manufacture ofas urea, ammonium sulfate, ammonium nitrate, or
their own end-products. The basic principles for theirdiammonium hydrogen phosphate. Ammonia is also
production and major uses are indicated here for eachused in the Solvay process, and it is a starting material
of these industries.for the manufacture of cyanides and nitriles (which are
Inorganic chemicals produced on an industrial scale canused to make polymers such as nylon and acrylics) as
be easily identified. Many of today's large companieswell as aromatic compounds containing nitrogen, such
started as producers of inorganics, but as coal—andas pyridine and aniline. The other source of nitrogen
especially petroleum—became important sources ofcompounds in the chemical industry is nitric acid,
raw materials; they were integrated into the productobtained from the oxidation of ammonia: 4NH3 + 5O2
chain. Inorganic chemicals such as chlorine are used in→ 4NO + 6H2O; 3NO + 3/2O2 → 3NO2 and
the manufacturing of several chlorides, including PVC3NO2 + H2O → 2HNO3 + NO
and hydrochloric acid.The first reaction is run over platinum-rhodium catalysts
There are many different sources of raw materialsat around 900°C (1,652°F). In the second and third
for the manufacture of inorganic chemicals. Very fewstages, a mixture of nitric oxide and air circulates
of them are found in their elemental form. Sulfur is athrough condensers, where it is partially oxidized. The
notable exception. It occurs in underground depositsnitrogen dioxide is absorbed in a tower, and nitric acid
and can be brought to the surface by compressed airsinks to the bottom. Nitric acid is mainly used to make
after it is melted by superheated steam. However,ammonium nitrate, most of it for fertilizer although it
increasing quantities of sulfur are recovered fromalso goes into the production of explosives. Nitration is
petroleum and natural gas (where they occur asused to manufacture explosives such as nitroglycerine
impurities). Air contains molecular nitrogen and oxygen.and trinitrotoluene (TNT) as well as many important
They may be separated by liquefaction and fractionalchemical intermediates used in the pharmaceutical and
distillation along with inert gases, especially argon. Saltdyestuff industries.
or brine can be used as sources of chlorine andThe world's major source of phosphorus is apatite, a
sometimes bromine, sodium hydroxide, and sodiumclass of phosphate minerals. Commercially, the most
carbonate, whereas metals such as iron, aluminum,important is fluoroapatite, a calcium phosphate that
copper, or titanium as well as phosphors, potassium,contains fluorine. This fluorine must be removed for the
calcium, and fluorine are obtained from mineral ores.manufacture of phosphoric acid, but it also can be
Saltpeter was once an important source of nitrogenused to produce hydrofluoric acid and fluorinated
compounds, but today most ammonia and nitrates arecompounds. Phosphoric acid is the starting material for
produced synthetically from nitrogen gas in the air.most of the phosphates that are produced industrially.
Recovery and recycling provide increasing amounts ofIt is obtained from the reaction of the apatite mineral
some metals. As environmental concerns increase,with sulfuric acid. Silica is present in the mineral as an
these operations will probably become an importantimpurity, and it reacts with hydrofluoric acid to yield
source of materials used in the manufacture of certainsilicon tetrafluoride, which can be converted to
inorganic chemicals.fluorosilicic acid, an important source of fluorine. More
The origins of the chemical industry can be traced tothan half of the phosphoric acid that is produced by
the Industrial Revolution. Sulfuric acid and sodiumthe reaction of phosphates with sulfuric acid is
carbonate were among the first industrial chemicals.converted directly to sodium or ammonium phosphates
"Oil of vitriol" (as the former was known) played anto be used as fertilizer; thus, purity is not a concern.
important role in the manipulation of metals, but itsFor products that require high purity, such as
production on an industrial scale required thedetergents and foodstuffs, phosphoric acid is produced
development of materials that would resist attack.from elemental phosphorus (at about four times the
Sodium carbonate was obtained in its anhydrous form,cost). An electric furnace operating at
"soda ash," from vegetable material until the quantities1,400–1,500°C (2,552–2,732°F) is used to form
produced could no longer meet the rapidly expandinga molten mass of apatite and silica that reacts with
needs of manufacturers of glass, soap, and textiles.coke and reduces the phosphate mineral:
This led the Royal Academy of Sciences of Paris, in2Ca3 (PO4)2 + 6SiO2 + 10C → P4 + 6CaSiO3 +
1775, to establish a contest for the discovery of a10CO
process based on an abundant raw material, sodiumConcentrating phosphoric acid leads to polyphosphoric
chloride, and to Nicolas Leblanc's method for theacid, a mixture of several polymeric species, a good
preparation of soda by converting salt into sulfate:catalyst and dehydrating agent. Polyphosphate salts
2NaCl + H2SO4 → Na2SO4 + 2HCl; followed byare used as water softeners in detergents or as
conversion of the sulfate to soda with charcoal andbuffers in food. Small quantities of elemental
chalk: Na2SO4 + 2C + CaCO3 → Na2CO3 + CaSphosphorus are used to make matches, and
+ 2CO2phosphorus halides to prepare specialty chemicals for
Although he did not win the prize, Leblanc's process isthe pharmaceutical and agrochemical industries.
associated with the birth of industrial chemistry. TheIndustries producing chlorine, sodium hydroxide (also
industrial production of chemicals was usually based onknown as caustic soda), sodium carbonate (or soda
running reactions that were known to yield the desiredash) and its derivatives and compounds based on
products on much larger scales. Success in thesecalcium oxide (or lime) are usually included under the
endeavors lay much more in the experience and skillchloralkali category. As both sodium hydroxide and
of their practitioners than the application of solidchlorine have a common raw material, sodium chloride,
chemical principles. This led to serious problems ofthey are produced in quantities that reflect their equal
control and the generation of noxious by-products. Themolar ratio, irrespective of the market for either
introduction of the Leblanc process in the northwest ofproduct. Since they are produced by electrolysis, they
England led to a general public outcry against the darkrequire a cheap source of brine and electricity:
and corrosive smoke that covered the surrounding2NaCl + 2H2O → 2NaOH + Cl2 + H2
countryside. The Alkali Act, passed in response in 1863,Most processes are based on the electrolysis of a
represents the first legislation that established emissionsodium chloride solution, but some plants operate with
standards.the molten salt. Three different cell types are used in
Sulfuric acid was an essential chemical for dyers,electrolysis in water: mercury cells, diaphragm cells, and
bleachers, and alkali manufacturers. Its production on amembrane cells. Membrane cells are replacing the
large scale required the development of lead-linedother two types in modern units, but it may not be
chambers that could resist the vapors which wereeconomically feasible to convert older plants.
formed when sulfur was burned with nitrates:Sodium hydroxide and sodium carbonate are
SO2 + NO2 + H2O → H2SO4 + NO, and NO + 1alternative sources of alkali, and their use has followed
2O2 → NO2the availability of raw materials as well as the
This process was wasteful and emitted corrosiveefficiency of processes developed for their production.
gases. It improved only in the mid-nineteenth centuryBoth require sodium chloride and energy and, if
when towers to recycle the gases were finallylimestone deposits are also available, sodium
introduced. The transportation of sulfuric acid wascarbonate may be produced by the Solvay process.
dangerous, and alkali manufacturers tended to produceLimestone consists mainly of calcium carbonate and
their own as a result. This marked the beginning of thecan be used to produce calcium oxide (or quicklime)
diversification and vertical integration that areand calcium hydroxide (or slaked lime); the oxide may
characteristic of the chemical industry. Sulfuric acidbe obtained by heating (1,200–1,500 ° C or
was also used in the manufacture of2,192–2,732 ° F) limestone, while the hydroxide,
superphosphates, which were produced as fertilizerswhich is more convenient to handle, is obtained by
on a large scale by the mid-nineteenth century. By thatadding water to the oxide: CaO + H2O → Ca(OH)2
time, a solution was found for the complex engineeringIts principal use is in steelmaking, but it also goes into
problems that had hampered the use of the alternativethe manufacture of chemicals, water treatment, and
process to produce soda:pollution control. In the Solvay process, calcium
NH3 + H2O + CO2 → NH4HCO3carbonate and sodium chloride are used to produce
NaCl + NH4HCO3 → NaHCO3 + NH4Clcalcium chloride and sodium carbonate with ammonia
2 NaHCO3 → Na2CO3 + H2O + CO2(which is recycled) as a medium for dissolving and
Ernest Solvay, a Belgian chemist, designed a tower incarbonating the sodium chloride and calcium hydroxide
which carbon dioxide reacted efficiently with solid salts.for precipitating calcium chloride from the solution.
The Solvay process had enormous advantages overAs sodium carbonate may be mined directly, its use
the Leblanc process: It did not generate as muchmay be preferred over a manufactured product. It is
waste and pollution; its raw materials, brine andused mainly in the glass industry. Sodium silicates may
ammonia, were readily available (the latter frombe derived from sodium carbonate and in their finely
gasworks); less fuel was used, and no sulfur or nitratedivided form, silica gel, may be used in detergents and
was involved. In spite of its higher capital costs, it wassoaps. Sodium hydroxide has many different uses in
rapidly adopted and soon became the major sourcethe chemical industry. Considerable amounts are used
of alkali.in the manufacture of paper and to make sodium
Another major process used in the manufacture ofhypochlorite for use in disinfectants and bleaches.
inorganic chemicals is the catalytic conversion ofChlorine is also used to produce vinyl chloride, the
nitrogen and hydrogen to ammonia. The Germanstarting material for the manufacture of polyvinyl
chemist Fritz Haber first synthesized ammonia fromchloride (PVC), and in water purification. Hydrochloric
nitrogen and hydrogen in 1909. Four years later,acid may be prepared by the direct reaction of
together with another German, Carl Bosch, he modifiedchlorine and hydrogen gas or by the reaction of
the process for the commercial production ofsodium chloride and sulfuric acid. It is used as a
ammonia. The Haber (or Haber–Bosch) processchlorinating agent for metals and organic compounds. In
represented a technological breakthrough since itcertain regions of the world, there are salt deposits or
required a very specialized plant to handle gases atbrines that have been enriched by bromine.
high pressures and temperatures.Commercially, bromine may be extracted by treating
Sulfuric acid has long been the chemical that isthe brines with chlorine and removing it by steam.
manufactured in the largest quantities on a world scale.Bromine is used in water disinfection; bleaching fibers
Its production is often linked to a country's stage ofand silk; and in the manufacture of medicinal bromine
development, owing to the large number ofcompounds and dyestuffs.
transformation processes in which it is used. SulfuricTitanium dioxide is by far the most important titanium
acid is manufactured from elemental sulfur. Mining wascompound. It can be purified by dissolving in sulfuric
the main source for this element, which was obtainedacid and precipitating the impurities. The solution is then
from sulfide-containing ores or in very pure form fromhydrolyzed, washed, and calcinated. Alternatively,
underground deposits by the Frasch process (injectionground rutile is chlorinated in the presence of carbon
of superheated steam and air into drillings and theand the resulting titanium tetrachloride is burned in
separation of the mixture that rises to the surface).oxygen to produce the chloride. Titanium dioxide is
The large-scale consumption of petroleum and naturalfound in nature in three crystal forms: anastase,
gas has changed this scenario since sulfur occurs asbrookite, and rutile. Its extreme whiteness and
an impurity in most fossil fuels and must be removedbrightness and its high index of refraction are
before the fuels are processed. These fuels areresponsible for its widespread use as a white pigment
presently the main source of sulfur, and their relativein paints, lacquers, paper, floor covering, plastics,
importance tends to increase with more rigorousrubbers, textiles, ceramics, and cosmetics.